Oxandrolone Uses, Side Effects & Warnings
Oxandrolone
What is oxandrolone?
Oxandrolone is a synthetic steroid medication primarily used to treat conditions related to muscle wasting, such as HIV-associated wasting syndrome and severe chronic kidney disease. It works by stimulating the body's production of growth hormones (GH) and insulin-like growth factor 1 (IGF-1), promoting muscle growth and fat loss.
Oxandrolone side effects
Common side effects include:
Edema (water retention)
Acute adversarial reactions (e.g., injection site pain, erythema, swelling)
Hyperglycemia (high blood sugar)
Mood changes
Gastrointestinal discomfort
Nausea and vomiting
Rapid weight gain
Related/similar drugs
Genotropin: A synthetic analog of human growth hormone.
Botox: Used for muscle relaxant purposes in certain conditions.
Marinol: A fat-soluble steroidal androgen.
Norditropin: A human growth hormone derivative.
Omnitrope: A synthetic analog of growth hormone-releasing hormone (GHRH).
Humatrope: Another synthetic growth hormone.
Warnings
Before taking this medicine
Always consult a healthcare provider before using oxandrolone. Use it with caution in patients with a history of hypersensitivity or allergic reactions to steroids, as well as those with conditions like high blood pressure, heart failure, or diabetes.
How should I take oxandrolone?
Oxandrolone is typically administered intramuscular (IM) once weekly. The dosage varies based on the patient's condition and response to treatment; it usually ranges from 50 mg to 200 mg per week, divided into 1-2 injections.
Oxandrolone dosing information
For adults with HIV-associated wasting or chronic kidney disease:
Starting dose: 50 mg IM once weekly
May be increased up to 100 mg or 200 mg depending on response and tolerance
What happens if I miss a dose?
If a dose is missed, take it as soon as remembered. If the next scheduled dose is within a few days, adjust accordingly; do not double up doses to avoid toxicity.
What happens if I overdose?
Overdose symptoms may include rapid weight gain, nausea, diarrhea, muscle pain, and fatigue. Seek immediate medical attention in such cases.
What should I avoid while taking oxandrolone?
Avoid excessive alcohol use to prevent dehydration and electrolyte imbalances.
Avoid sharing needles or using non-sterile equipment to prevent infections.
What other drugs will affect oxandrolone?
Oxandrolone may interact with:
Insulin or anti-diabetic agents (due to hyperglycemia risk)
Other corticosteroids and hormones
Ketogenic drugs
Electrolyte supplements (without medical supervision)
More about oxandrolone
Oxandrolone is not a controlled substance in most jurisdictions, though it may have some potential for abuse.
It is typically prescribed for short-term use due to its risk of side effects and dependence.
Patient resources
Always follow your healthcare provider's instructions regarding dosage and administration.
Inform your healthcare provider about all medications, supplements, or herbal products you are taking.
Other brands
Oxandrolone may be available under various brand names depending on the manufacturer and region. Always check the prescribing information for specific brand details.
Professional resources
US National Library of Medicine (NLM): Drugs.com - Oxandrolone (https://www.drugs.com/oxandrolone.html)
EuroGuide: May contain additional prescribing information relevant to European medical practices.
Related treatment guides
HIV and Chronic Wasting Syndrome Management
Kidney Disease Treatment Guidelines
References:
